Delta‐Like Protein 3 Expression and Targeting in Merkel Cell Carcinoma

PURPOSE: Delta‐like protein 3 (DLL3) is being developed as a predictive biomarker for DLL3‐targeting antibody‐drug conjugate and other therapies. Given the neuroendocrine features of Merkel cell carcinoma (MCC), we sought to evaluate DLL3 expression and its role in MCC. EXPERIMENTAL DESIGN: Formalin...

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Vydáno v:Oncologist
Hlavní autoři: Xie, Hao, Kaye, Frederic J., Isse, Kumiko, Sun, Yan, Ramoth, Johanna, French, Dorothy M., Flotte, Thomas J., Luo, Yan, Saunders, Laura R., Mansfield, Aaron S.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2020
Témata:
Melanoma and Cutaneous Malignancies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7485334/
https://ncbi.nlm.nih.gov/pubmed/32372416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2019-0877
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