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Mechanistic Quantitative Pharmacology Strategies for the Early Clinical Development of Bispecific Antibodies in Oncology

Bispecific antibodies (bsAbs) have become an integral component of the therapeutic research strategy to treat cancer. In addition to clinically validated immune cell re‐targeting, bsAbs are being designed for tumor targeting and as dual immune modulators. Explorative preclinical and emerging clinica...

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Detalhes bibliográficos
Publicado no:Clin Pharmacol Ther
Main Authors: Betts, Alison, van der Graaf, Piet H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484986/
https://ncbi.nlm.nih.gov/pubmed/32579234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1961
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