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Mechanistic Quantitative Pharmacology Strategies for the Early Clinical Development of Bispecific Antibodies in Oncology

Bispecific antibodies (bsAbs) have become an integral component of the therapeutic research strategy to treat cancer. In addition to clinically validated immune cell re‐targeting, bsAbs are being designed for tumor targeting and as dual immune modulators. Explorative preclinical and emerging clinica...

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Bibliografiske detaljer
Udgivet i:Clin Pharmacol Ther
Main Authors: Betts, Alison, van der Graaf, Piet H.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484986/
https://ncbi.nlm.nih.gov/pubmed/32579234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1961
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