Hyperconserved Elements in Human 5′UTRs Shape Essential Post-transcriptional Regulatory Networks

Post-transcriptional regulation (PTR) of gene expression is a powerful determinant of cellular phenotypes. The 5′ and 3′ untranslated regions of the mRNA (UTRs) mediate this role through sequence and secondary structure elements bound by RNA-binding proteins (RBPs) and non-coding RNAs. While functio...

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Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Zuccotti, Paola, Peroni, Daniele, Potrich, Valentina, Quattrone, Alessandro, Dassi, Erik
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Molecular Biosciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484617/
https://ncbi.nlm.nih.gov/pubmed/33005630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.00220
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