HDAC6 plays a non-canonical role in the regulation of anti-tumor immune responses, dissemination, and invasiveness of breast cancer.

Despite the outstanding clinical results of immune checkpoint blockade (ICB) in melanoma and other cancers, clinical trials in breast cancer have reported low responses to these therapies. Current efforts are now focused on improving the treatment efficacy of ICB in breast cancer using new combinati...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Banik, Debarati, Noonepalle, Satish, Hadley, Melissa, Palmer, Erica, Gracia-Hernandez, Maria, Zevallos-Delgado, Christian, Manhas, Namratta, Simonyan, Hayk, Young, Colin N., Popratiloff, Anastas, Chiappinelli, Katherine B., Fernandes, Rohan, Sotomayor, Eduardo M., Villagra, Alejandro
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484424/
https://ncbi.nlm.nih.gov/pubmed/32605998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-3738
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