Structure of the Human Respiratory Syncytial Virus M2-1 Protein in Complex with a Short Positive-Sense Gene-End RNA

The M2-1 protein of human respiratory syncytial virus (HRSV) is a transcription anti-terminator that regulates the processivity of the HRSV RNA-dependent RNA polymerase (RdRP). Here, we report a crystal structure of HRSV M2-1 bound to a short positive-sense gene-end RNA (SH7) at 2.7 Å resolution. We...

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Vydáno v:Structure
Hlavní autoři: Gao, Yunrong, Cao, Dongdong, Pawnikar, Shristi, John, Karen P., Ahn, Hyunjun Max, Hill, Shaylan, Ha, Ju Mi, Parikh, Priyal, Ogilvie, Claire, Swain, Anshuman, Yang, Amy, Bell, Amber, Salazar, Angela, Miao, Yinglong, Liang, Bo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484405/
https://ncbi.nlm.nih.gov/pubmed/32697936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.07.001
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