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6-Formylindolo (3, 2-b) Carbazole (FICZ)–mediated protection of gut barrier is dependent on T cells in a mouse model of alcohol combined with burn injury

6-Formylindolo (3, 2-b) Carbazole (FICZ) is a ligand of aryl hydrocarbon receptor (AHR) which regulates Th17 release of IL-17 and IL-22 production. Earlier, we showed that ethanol combined with burn injury suppresses Th17 responses and disrupts intestinal barrier leading to increased gut bacterial g...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta Mol Basis Dis
Main Authors: Li, Xiaoling, Luck, Marisa E., Hammer, Adam M., Cannon, Abigail R., Choudhry, Mashkoor A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484351/
https://ncbi.nlm.nih.gov/pubmed/32711051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2020.165901
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