Genetic disruption of the inflammasome adaptor ASC has minimal impact on the pathogenesis of Duchenne muscular dystrophy in mdx Mice

AIM: Up-regulation of inflammasome proteins was reported in dystrophin-deficient muscles. However, it remains to be determined whether inflammasome activation plays a role in the pathogenesis of Duchenne muscular dystrophy. This study was therefore set out to investigate whether genetic disruption o...

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Bibliografiske detaljer
Udgivet i:Life Sci
Main Authors: Lau, Yeh Siang, Zhao, Lixia, Zhang, Chen, Li, Haiwen, Han, Renzhi
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484256/
https://ncbi.nlm.nih.gov/pubmed/32659370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2020.118069
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