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Viral Delivery of Multiple miRNA Promotes Retinal Ganglion Cell Survival and Functional Preservation after Optic Nerve Crush Injury

Bone marrow mesenchymal stem cell (BMSC)-derived small extracellular vesicles (sEV) but not fibroblast sEV provide retinal ganglion cell (RGC) neuroprotection both in vitro and in vivo, with miRNAs playing an essential role. More than 40 miRNAs were more abundant in BMSC-sEV than in fibroblast-sEV....

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Detalhes bibliográficos
Publicado no:Exp Eye Res
Main Authors: Mead, Ben, Cullather, Erin, Nakaya, Naoki, Niu, Yuzhe, Kole, Christo, Ahmed, Zubair, Tomarev, Stanislav
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484142/
https://ncbi.nlm.nih.gov/pubmed/32574667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108071
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