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A Longitudinal Examination of Plasma Neurofilament Light and Total Tau for the Clinical Detection and Monitoring of Alzheimer’s Disease

We examined baseline and longitudinal associations between plasma neurofilament light (NfL) and total tau (t-tau), and the clinical presentation of Alzheimer’s disease (AD). 579 participants (238, normal cognition [NC]; 185, mild cognitive impairment [MCI]; 156, AD dementia) had baseline blood draws...

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Veröffentlicht in:Neurobiol Aging
Hauptverfasser: Sugarman, Michael A., Zetterberg, Henrik, Blennow, Kaj, Tripodis, Yorghos, McKee, Ann C., Stein, Thor D., Martin, Brett, Palmisano, Joseph N., Steinberg, Eric G., Simkin, Irene, Budson, Andrew E., Killiany, Ronald, O’Connor, Maureen K., Au, Rhoda, Qiu, Wendy Wei Qiao, Goldstein, Lee E., Kowall, Neil W., Mez, Jesse, Stern, Robert A., Alosco, Michael L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484086/
https://ncbi.nlm.nih.gov/pubmed/32585491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.05.011
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