Predictive pharmacogenetic biomarkers for breast cancer recurrence prevention by simvastatin

BACKGROUND: Statins treat hyperlipidemia and prevent cardiovascular morbidity and mortality. Evidence suggests that they also have anti-neoplastic activity. Several studies show a reduced rate of breast cancer recurrence among lipophilic statin users (e.g., simvastatin), motivating calls for clinica...

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Pubblicato in:Acta Oncol
Autori principali: Ahern, Thomas P., Damkier, Per, Feddersen, Søren, Kjærsgaard, Anders, Lash, Timothy L., Hamilton-Dutoit, Stephen, Lythjohan, Cathrine Bredal, Ejlertsen, Bent, Christiansen, Peer M., Cronin-Fenton, Deirdre P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483991/
https://ncbi.nlm.nih.gov/pubmed/32351149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0284186X.2020.1759820
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