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Evaluation of a Paradigm Shift From Intravenous Antibiotics to Oral Step-Down Therapy for the Treatment of Infective Endocarditis: A Narrative Review

IMPORTANCE: The requirement of prolonged intravenous antibiotic courses to treat infective endocarditis (IE) is a time-honored dogma of medicine. However, numerous antibiotics are now available that achieve adequate levels in the blood after oral administration to kill bacteria. Moreover, prolonged...

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Publicat a:JAMA Intern Med
Autors principals: Spellberg, Brad, Chambers, Henry F., Musher, Daniel M., Walsh, Thomas L., Bayer, Arnold S.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483894/
https://ncbi.nlm.nih.gov/pubmed/32227127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamainternmed.2020.0555
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