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Contrasting effects of B cell depletion on CD4(+) and CD8(+) memory T cell responses generated after transplantation

Alloreactive memory T cells play a key role in transplantation by accelerating allograft rejection and preventing tolerance induction. Some studies using μMT mice, which are constitutionally devoid of B cells, showed that B cells were required for the generation of memory T cells after allotransplan...

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Detalles Bibliográficos
Publicado en:Am J Transplant
Autores principales: Marino, Jose, Gonzalez-Nolasco, Bruno, Wang, Xianding, Orent, William, Benichou, Gilles
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483880/
https://ncbi.nlm.nih.gov/pubmed/32185859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15858
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