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Artificial iron hydrogenase made by covalent grafting of Knölker’s complex into xylanase: Application in asymmetric hydrogenation of an aryl ketone in water

We report a new artificial hydrogenase made by covalent anchoring of the iron Knölker’s complex to a xylanase S212C variant. This artificial metalloenzyme was found to be able to catalyze efficiently the transfer hydrogenation of the benchmark substrate trifluoroacetophenone by sodium formate in wat...

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Publicat a:Biotechnol Appl Biochem
Autors principals: KARIYAWASAM, Kalani, GHATTAS, Wadih, DE LOS SANTOS, Yossef López, DOUCET, Nicolas, GAILLARD, Sylvain, RENAUD, Jean-Luc, AVENIER, Frédéric, MAHY, Jean-Pierre, RICOUX, Rémy
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483719/
https://ncbi.nlm.nih.gov/pubmed/32134142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bab.1906
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