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Improving the clinical significance of preclinical immunotherapy studies through incorporating tumor microenvironment-like conditions

Frequently the results generated when testing novel anti-tumor immunotherapies in vitro do not correlate with data collected in in vivo models and/or in clinical settings. It is our hypothesis that this discrepancy is caused by the use of in vitro conditions, such as normoxia, a two-dimensional surf...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Maggs, Luke, Ferrone, Soldano
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483623/
https://ncbi.nlm.nih.gov/pubmed/32571789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-0358
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