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Local anesthesia enhanced with increasing high-frequency ultrasound intensity

The effect of local anesthetics, particularly those which are hydrophilic, such as tetrodotoxin, is impeded by tissue barriers that restrict access to individual nerve cells. Methods of enhancing penetration of tetrodotoxin into nerve include co-administration with chemical permeation enhancers, nan...

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Detalles Bibliográficos
Publicado en:Drug Deliv Transl Res
Main Authors: Cullion, Kathleen, Petishnok, Laura C., Sun, Tao, Santamaria, Claudia M., Pemberton, Grant L., McDannold, Nathan J., Kohane, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483597/
https://ncbi.nlm.nih.gov/pubmed/32307675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-020-00760-1
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