Humanized single domain antibodies neutralize SARS-CoV-2 by targeting the spike receptor binding domain

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads worldwide and leads to an unprecedented medical burden and lives lost. Neutralizing antibodies provide efficient blockade for viral infection and are a promising category of biological therapies. Here, using SARS-CoV-2 spike recept...

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Vydáno v:Nat Commun
Hlavní autoři: Chi, Xiaojing, Liu, Xiuying, Wang, Conghui, Zhang, Xinhui, Li, Xiang, Hou, Jianhua, Ren, Lili, Jin, Qi, Wang, Jianwei, Yang, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483421/
https://ncbi.nlm.nih.gov/pubmed/32913273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18387-8
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