Influence of apolipoprotein-E genotype on brain amyloid load and longitudinal trajectories

To characterize the influence of APOE genotype on cerebral Aβ load and longitudinal Aβ trajectories, [(11)C]PiB PET imaging studies were performed in a cohort of 428 participants with known APOE genotype and a range of clinical diagnoses from cognitively normal elderly to Alzheimer’s disease (AD). [...

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Udgivet i:Neurobiol Aging
Main Authors: Lopresti, Brian J ., Campbell, Elizabeth M., Yu, Zheming, Anderson, Stewart J., Cohen, Ann D., Minhas, Davneet S., Snitz, Beth E., Royse, Sarah K., Becker, Carl R., Aizenstein, Howard J., Mathis, Chester A., Lopez, Oscar L., Klunk, William E., Tudorascu, Dana L.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483397/
https://ncbi.nlm.nih.gov/pubmed/32603776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2020.05.012
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