Genetic Analyses Support the Contribution of mRNA N(6)-methyladenosine (m(6)A) Modification to Human Disease Heritability

N(6)-methyladenosine (m(6)A) plays important roles in regulating mRNA processing. Despite rapid progress in this field, little is known about genetic determinants of m(6)A modification and their role in common diseases. In this work, we mapped quantitative trait loci (QTLs) of m(6)A peaks in 60 Yoru...

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Detalhes bibliográficos
Publicado no:Nat Genet
Main Authors: Zhang, Zijie, Luo, Kaixuan, Zou, Zhongyu, Qiu, Maguanyun, Tian, Jiakun, Sieh, Laura, Shi, Hailing, Zou, Yuxin, Wang, Gao, Morrison, Jean, Zhu, Allen C., Qiao, Min, Li, Zhongshan, Stephens, Matthew, He, Xin, He, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483307/
https://ncbi.nlm.nih.gov/pubmed/32601472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-0644-z
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