Inhibition of LSD1 in MDS Progenitors Restores Differentiation of CD141(Hi) Conventional Dendritic Cells

The use of immunotherapy to treat patients with myelodysplastic syndromes (MDS) shows promise but is limited by our incomplete understanding of the immunologic milieu. In solid tumors, CD141(Hi) conventional dendritic cells (CD141(Hi) cDCs) are necessary for anti-tumor immunosurveillance and the res...

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Publicat a:Leukemia
Autors principals: Srivastava, Pragya, Tzetzo, Stephanie L., Gomez, Eduardo Cortes, Eng, Kevin H., Sait, Sheila N. Jani, Kuechle, Joseph B., Singh, Prashant K., De Jong, Kitty, Wiatrowski, Kyle R., Peresie, Jennifer, Dimitroff, Ava, Lynch, Miranda L., Wang, Jianmin, Abrams, Scott I., Griffiths, Elizabeth A., Nemeth, Michael J.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483249/
https://ncbi.nlm.nih.gov/pubmed/32099035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-020-0765-5
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