Contributions of IFN-γ and granulysin to the clearance of Plasmodium yoelii blood stage

P. vivax-infected Retics (iRetics) express human leukocyte antigen class I (HLA-I), are recognized by CD8(+) T cells and killed by granulysin (GNLY) and granzymes. However, how Plasmodium infection induces MHC-I expression on Retics is unknown. In addition, whether GNLY helps control Plasmodium infe...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Hojo-Souza, Natália Satchiko, de Azevedo, Patrick Orestes, de Castro, Júlia Teixeira, Teixeira-Carvalho, Andréa, Lieberman, Judy, Junqueira, Caroline, Gazzinelli, Ricardo Tostes
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7482970/
https://ncbi.nlm.nih.gov/pubmed/32913355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008840
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