Concomitant genetic alterations are associated with response to EGFR targeted therapy in patients with lung adenocarcinoma

BACKGROUND: Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are considered to be more effective than chemotherapy in the treatment of EGFR-mutant advanced non-small cell lung cancer (NSCLC). However, in addition to EGFR-sensitive mutations, the genetic factors that affect the...

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Enregistré dans:
Détails bibliographiques
Publié dans:Transl Lung Cancer Res
Auteurs principaux: Chen, Hualin, Liu, Meilian, Dai, Zhiwei, Li, Shujun, Luo, Yiping, Wang, Yongcun, Su, Wenmei, Cai, Weijing, Yang, Donghong, Huang, Jian, Yang, Zhixiong
Format: Artigo
Langue:Inglês
Publié: AME Publishing Company 2020
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481595/
https://ncbi.nlm.nih.gov/pubmed/32953500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-20-679
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