EGFR circulating tumour DNA testing: identification of predictors of ctDNA detection and implications for survival outcomes

BACKGROUND: EGFR T790M testing is the standard of care for activating EGFR mutation (EGFRm) non-small cell lung cancer (NSCLC) progressing on 1st/2nd generation TKIs to select patients for osimertinib. Despite sensitive assays, detection of circulating tumour deoxyribonucleic acid (ctDNA) is variabl...

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Vydáno v:Transl Lung Cancer Res
Hlavní autoři: Pender, Alexandra, Hughesman, Curtis, Law, Elaine, Kristanti, Amadea, McNeil, Kelly, Wong, Selina, Tucker, Tracy, Bosdet, Ian, Young, Sean, Laskin, Janessa, Karsan, Aly, Yip, Stephen, Ho, Cheryl
Médium: Artigo
Jazyk:Inglês
Vydáno: AME Publishing Company 2020
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7481591/
https://ncbi.nlm.nih.gov/pubmed/32953487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr-19-581
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