Differentiation of human intestinal organoids with endogenous vascular endothelial cells

Human pluripotent stem cell (hPSC)-derived intestinal organoids (HIOs) lack some cellular populations found in the native organ, including vasculature. Using single cell RNA sequencing (scRNA-seq), we have identified a population of endothelial cells (ECs) present early in HIO differentiation that d...

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Foilsithe in:Dev Cell
Main Authors: Holloway, Emily M., Wu, Joshua H., Czerwinkski, Michael, Sweet, Caden W., Wu, Angeline, Tsai, Yu-Hwai, Huang, Sha, Stoddard, Amy E., Capeling, Meghan M., Glass, Ian, Spence, Jason R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480827/
https://ncbi.nlm.nih.gov/pubmed/32841595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.07.023
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