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Generation of reactive oxygen species by hydroxypyridone compound/iron complexes

Objectives: Prooxidant properties of iron-binding hydroxypyridone compounds including deferiprone and mimosine were analyzed. Methods: Hydroxypyridone/iron-dependent production of reactive oxygen species was evidenced by the inactivation of aconitase, the most sensitive enzyme to oxidative stress in...

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Detalhes bibliográficos
Publicado no:Redox Rep
Main Authors: Murakami, Keiko, Yoshino, Masataka
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480593/
https://ncbi.nlm.nih.gov/pubmed/32615878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13510002.2020.1787662
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