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Increased small extracellular vesicle secretion after chemotherapy via upregulation of cholesterol metabolism in acute myeloid leukaemia

Most patients with acute myeloid leukaemia (AML) experience disease recurrence after chemotherapy largely due to the development of drug resistance. Small extracellular vesicles (sEVs) are known to play a significant role in leukaemia drug resistance by delivery of anti-apoptotic proteins and genes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Extracell Vesicles
Hauptverfasser: Hong, Chang-Sook, Jeong, Emily, Boyiadzis, Michael, Whiteside, Theresa L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480590/
https://ncbi.nlm.nih.gov/pubmed/32944189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2020.1800979
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