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Increased small extracellular vesicle secretion after chemotherapy via upregulation of cholesterol metabolism in acute myeloid leukaemia

Most patients with acute myeloid leukaemia (AML) experience disease recurrence after chemotherapy largely due to the development of drug resistance. Small extracellular vesicles (sEVs) are known to play a significant role in leukaemia drug resistance by delivery of anti-apoptotic proteins and genes...

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Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Hong, Chang-Sook, Jeong, Emily, Boyiadzis, Michael, Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480590/
https://ncbi.nlm.nih.gov/pubmed/32944189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2020.1800979
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