Dendritic cell derived exosomes loaded with immunoregulatory cargo reprogram local immune responses and inhibit degenerative bone disease in vivo

Chronic bone degenerative diseases represent a major threat to the health and well-being of the population, particularly those with advanced age. This study isolated exosomes (EXO), natural nano-particles, from dendritic cells, the “directors” of the immune response, to examine the immunobiology of...

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Veröffentlicht in:J Extracell Vesicles
Hauptverfasser: Elashiry, Mahmoud, Elashiry, Mohamed M., Elsayed, Ranya, Rajendran, Mythily, Auersvald, Carol, Zeitoun, Rana, Rashid, Mohammad H., Ara, Roxan, Meghil, Mohamed M., Liu, Yutao, Arbab, Ali S., Arce, Roger M., Hamrick, Mark, Elsalanty, Mohammed, Brendan, Marshall, Pacholczyk, Rafal, Cutler, Christopher W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480413/
https://ncbi.nlm.nih.gov/pubmed/32944183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/20013078.2020.1795362
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