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A neutrophil activation signature predicts critical illness and mortality in COVID-19

Pathologic immune hyperactivation is emerging as a key feature of critical illness in COVID-19, but the mechanisms involved remain poorly understood. We carried out proteomic profiling of plasma from cross-sectional and longitudinal cohorts of hospitalized patients with COVID-19 and analyzed clinica...

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Veröffentlicht in:medRxiv
Hauptverfasser: Meizlish, Matthew L., Pine, Alexander B., Bishai, Jason D., Goshua, George, Nadelmann, Emily R., Simonov, Michael, Chang, C-Hong, Zhang, Hanming, Shallow, Marcus, Bahel, Parveen, Owusu, Kent, Yamamoto, Yu, Arora, Tanima, Atri, Deepak S., Patel, Amisha, Gbyli, Rana, Kwan, Jennifer, Won, Christine H., Dela Cruz, Charles, Price, Christina, Koff, Jonathan, King, Brett A., Rinder, Henry M., Wilson, F. Perry, Hwa, John, Halene, Stephanie, Damsky, William, van Dijk, David, Lee, Alfred Ian, Chun, Hyung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480036/
https://ncbi.nlm.nih.gov/pubmed/32908988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.09.01.20183897
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