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High MHC-II expression in Epstein–Barr virus-associated gastric cancers suggests that tumor cells serve an important role in antigen presentation

EBV-associated gastric adenocarcinomas (EBVaGCs) often exhibit better clinical outcomes than EBV negative gastric cancers (GCs), which could be related to their consistent expression of foreign viral antigens. Antigen-presenting cells (APCs) present peptide antigens in the context of the class-II ma...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ghasemi, Farhad, Tessier, Tanner M., Gameiro, Steven F., Maciver, Allison H., Cecchini, Matthew J., Mymryk, Joe S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479113/
https://ncbi.nlm.nih.gov/pubmed/32901107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71775-4
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