Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness

Blindness arising from retinal or macular degeneration results in significant social, health and economic burden. While approved treatments exist for neovascular (‘wet’) age-related macular degeneration, new therapeutic targets/interventions are needed for the more prevalent atrophic (‘dry’) form of...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Sundaramurthi, Husvinee, Roche, Sarah L., Grice, Guinevere L., Moran, Ailis, Dillion, Eugene T., Campiani, Giuseppe, Nathan, James A., Kennedy, Breandán N.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479070/
https://ncbi.nlm.nih.gov/pubmed/32984302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00689
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