Autologous tumor cell vaccine induces antitumor T cell immune responses in patients with mantle cell lymphoma: A phase I/II trial

Here, we report on the results of a phase I/II trial (NCT00490529) for patients with mantle cell lymphoma who, having achieved remission after immunochemotherapy, were vaccinated with irradiated, CpG-activated tumor cells. Subsequently, vaccine-primed lymphocytes were collected and reinfused after a...

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Publicado no:J Exp Med
Main Authors: Frank, Matthew J., Khodadoust, Michael S., Czerwinski, Debra K., Haabeth, Ole A.W., Chu, Michael P., Miklos, David B., Advani, Ranjana H., Alizadeh, Ash A., Gupta, Neel K., Maeda, Lauren S., Reddy, Sunil A., Laport, Ginna G., Meyer, Everett H., Negrin, Robert S., Rezvani, Andrew R., Weng, Wen-Kai, Sheehan, Kevin, Faham, Malek, Okada, Ami, Moore, A. Holliston, Phillips, Destiny L., Wapnir, Irene L., Brody, Joshua D., Levy, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478738/
https://ncbi.nlm.nih.gov/pubmed/32558897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191712
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