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First-line pemetrexed and carboplatin plus anlotinib for epidermal growth factor receptor wild-type and anaplastic lymphoma kinase-negative lung adenocarcinoma with brain metastasis: A case report and review of the literature

RATIONALE: Brain metastasis (BM) is a serious complication in non-small cell lung cancer (NSCLC) patients. Pemetrexed is one of the preferred agents in nonsquamous NSCLC with BM; however, the traditional chemotherapy demonstrated limited efficacy partly due to drug resistance and the blood-brain bar...

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Publicado en:Medicine (Baltimore)
Main Authors: Zhang, Chu, Kong, Feng-Wei, Wu, Wen-Bin, Zhang, Miao, Yu, Guang-Mao, Wang, Xiang, Liu, Yuan-Yuan
Formato: Artigo
Idioma:Inglês
Publicado: Lippincott Williams & Wilkins 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478551/
https://ncbi.nlm.nih.gov/pubmed/32899099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000022128
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