FAM46B Promotes Apoptosis and Inhibits Glycolysis of Prostate Cancer Through Inhibition of the MYC-LDHA Axis

OBJECTIVE: Increased dependence on glycolysis is a known element of cancer. This study was designed to examine critical glycolysis components including transcription factor MYC and its downstream target lactate dehydrogenase A (LDHA), potential upstream regulators of glycolysis such as family with s...

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Bibliographische Detailangaben
Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Liang, Tao, Ye, Xuxiao, Yan, Dongliang, Deng, Chao, Li, Zuowei, Tian, Binqiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7478375/
https://ncbi.nlm.nih.gov/pubmed/32943883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S258724
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