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The ghosts in the machine: DNA methylation and the mystery of differentiation
Methylation regulates DNA by altering chromatin and limiting accessibility of transcription factors and RNA polymerase. In this way, DNA methylation controls gene expression and plays a role in ES cell regulation, tissue differentiation and the development of the organism. In abnormal circumstances...
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| Veröffentlicht in: | Biochim Biophys Acta |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7477944/ https://ncbi.nlm.nih.gov/pubmed/22381140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2012.02.013 |
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