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Mesenchymal Stem Cells Decrease M1/M2 Ratio and Alleviate Inflammation to Improve Limb Ischemia in Mice

BACKGROUND: Limb ischemia (LI) is the underlying pathology of peripheral artery disease (PAD). Macrophages play a critical role in inflammation and can contribute to the exacerbation or reduction of inflammation. Transplantation of mesenchymal stem cells (MSCs) is an emerging therapeutic strategy fo...

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Detalles Bibliográficos
Publicado en:Med Sci Monit
Main Authors: Song, Ye, Zhang, Tian-Jie, Li, Yuan, Gao, Yuan
Formato: Artigo
Idioma:Inglês
Publicado: International Scientific Literature, Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477932/
https://ncbi.nlm.nih.gov/pubmed/32860388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.923287
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