High-density lipoproteins induce miR-223-3p biogenesis and export from myeloid cells: Role of scavenger receptor BI-mediated lipid transfer

BACKGROUND AND AIMS: We recently showed that miR-223–3p on high-density lipoproteins (HDL) is exported to endothelial cells, where it inhibits inflammation. However, the origin of miR-2233p on HDL is unknown. We hypothesize that HDL-associated miR-223–3p originates in myeloid cells and is exported t...

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Veröffentlicht in:Atherosclerosis
Hauptverfasser: Torres, Luisa F. Cuesta, Zhu, Wanying, Öhrling, Gustav, Larsson, Rasmus, Patel, Mili, Wiese, Carrie B., Rye, Kerry-Anne, Vickers, Kasey C., Tabet, Fatiha
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477814/
https://ncbi.nlm.nih.gov/pubmed/31096070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2019.04.227
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