Changes in nano-mechanical properties of human epidermal cornified cells in children with atopic dermatitis

Background: Impaired skin barrier is an important etiological factor in atopic dermatitis (AD). The structural protein filaggrin (FLG) plays a major role in maintenance of the competent skin barrier and its deficiency is associated with enhanced susceptibility to mechanical injury. Here we examined...

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Publicat a:Wellcome Open Res
Autors principals: Haftek, Marek, McAleer, Maeve A, Jakasa, Ivone, McLean, WH Irwin, Kezic, Sanja, Irvine, Alan D.
Format: Artigo
Idioma:Inglês
Publicat: F1000 Research Limited 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477645/
https://ncbi.nlm.nih.gov/pubmed/32954014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.15729.2
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