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Cocaine-mediated circadian reprogramming in the striatum through dopamine D2R and PPARγ activation

Substance abuse disorders are linked to alteration of circadian rhythms, although the molecular and neuronal pathways implicated have not been fully elucidated. Addictive drugs, such as cocaine, induce a rapid increase of dopamine levels in the brain. Here, we show that acute administration of cocai...

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Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Brami-Cherrier, Karen, Lewis, Robert G., Cervantes, Marlene, Liu, Yu, Tognini, Paola, Baldi, Pierre, Sassone-Corsi, Paolo, Borrelli, Emiliana
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477550/
https://ncbi.nlm.nih.gov/pubmed/32895370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18200-6
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