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PM2.5 downregulates MicroRNA-139-5p and induces EMT in Bronchiolar Epithelium Cells by targeting Notch1

PM2.5 was closely linked to lung cancer worldwide. However, the mechanism involved in PM2.5 induced lung cancer is still largely unknown. In this study, we performed chronic PM2.5 stimulation animal and cells model to investigate the carcinogenetic mechanisms of PM2.5 by targeting EMT through Notch1...

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Detalhes bibliográficos
Publicado no:J Cancer
Main Authors: Wang, Yunxia, Zhong, Yijue, Zhang, Cheng, Liao, Jiping, Wang, Guangfa
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477455/
https://ncbi.nlm.nih.gov/pubmed/32913469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.46976
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