Knockout of EGFL6 by CRISPR/Cas9 Mediated Inhibition of Tumor Angiogenesis in Ovarian Cancer

Tumor angiogenesis plays an important role in the progression and metastasis of ovarian cancer. EGFL6 protein is highly expressed in ovarian cancer and has been proposed to play an important role in promoting tumor angiogenesis. Here, a CRISPR/Cas9 system was used to knockout the EGFL6 gene in the o...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Zhu, Wenhui, Liu, Chunyan, Lu, Tongyi, Zhang, Yinmei, Zhang, Simin, Chen, Qi, Deng, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477343/
https://ncbi.nlm.nih.gov/pubmed/32983976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01451
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