PORCN Negatively Regulates AMPAR Function Independently of Subunit Composition and the Amino-Terminal and Carboxy-Terminal Domains of AMPARs

Most fast excitatory synaptic transmissions in the mammalian brain are mediated by α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors (AMPARs), which are ligand-gated cation channels. The membrane expression level of AMPARs is largely determined by auxiliary subunits in AMPAR macromolecu...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Wei, Mengping, Wang, Meng, Wang, Jue, Su, Feng, Wang, Yangzhen, Sun, Meng, Wang, Shanshan, Liu, Mengna, Wang, Hongyi, Lu, Mingyang, Li, Wei, Gong, Yutian, Yang, Lei, Zhang, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477090/
https://ncbi.nlm.nih.gov/pubmed/32984326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00829
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