Sodium New Houttuyfonate Inhibits Candida albicans Biofilm Formation by Inhibiting the Ras1-cAMP-Efg1 Pathway Revealed by RNA-seq

Here, we aim to investigate the antifungal effect and mechanism of action of sodium new houttuyfonate (SNH) against Candida albicans. Microdilution analysis results showed that SNH possesses potent inhibitory activity against C. albicans SC5314, with a MIC(80) of 256 μg/mL. Furthermore, we found tha...

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Foilsithe in:Front Microbiol
Main Authors: Wu, Jiadi, Wu, Daqiang, Zhao, Yeye, Si, Yuanqing, Mei, Longfei, Shao, Jing, Wang, Tianming, Yan, Guiming, Wang, Changzhong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020
Ábhair:
Microbiology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477049/
https://ncbi.nlm.nih.gov/pubmed/32983053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.02075
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