Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk

Accurate colorectal cancer (CRC) risk prediction models are critical for identifying individuals at low and high risk of developing CRC, as they can then be offered targeted screening and interventions to address their risks of developing disease (if they are in a high-risk group) and avoid unnecess...

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Publicat a:Am J Hum Genet
Autors principals: Thomas, Minta, Sakoda, Lori C., Hoffmeister, Michael, Rosenthal, Elisabeth A., Lee, Jeffrey K., van Duijnhoven, Franzel J.B., Platz, Elizabeth A., Wu, Anna H., Dampier, Christopher H., de la Chapelle, Albert, Wolk, Alicja, Joshi, Amit D., Burnett-Hartman, Andrea, Gsur, Andrea, Lindblom, Annika, Castells, Antoni, Win, Aung Ko, Namjou, Bahram, Van Guelpen, Bethany, Tangen, Catherine M., He, Qianchuan, Li, Christopher I., Schafmayer, Clemens, Joshu, Corinne E., Ulrich, Cornelia M., Bishop, D. Timothy, Buchanan, Daniel D., Schaid, Daniel, Drew, David A., Muller, David C., Duggan, David, Crosslin, David R., Albanes, Demetrius, Giovannucci, Edward L., Larson, Eric, Qu, Flora, Mentch, Frank, Giles, Graham G., Hakonarson, Hakon, Hampel, Heather, Stanaway, Ian B., Figueiredo, Jane C., Huyghe, Jeroen R., Minnier, Jessica, Chang-Claude, Jenny, Hampe, Jochen, Harley, John B., Visvanathan, Kala, Curtis, Keith R., Offit, Kenneth, Li, Li, Le Marchand, Loic, Vodickova, Ludmila, Gunter, Marc J., Jenkins, Mark A., Slattery, Martha L., Lemire, Mathieu, Woods, Michael O., Song, Mingyang, Murphy, Neil, Lindor, Noralane M., Dikilitas, Ozan, Pharoah, Paul D.P., Campbell, Peter T., Newcomb, Polly A., Milne, Roger L., MacInnis, Robert J., Castellví-Bel, Sergi, Ogino, Shuji, Berndt, Sonja I., Bézieau, Stéphane, Thibodeau, Stephen N., Gallinger, Steven J., Zaidi, Syed H., Harrison, Tabitha A., Keku, Temitope O., Hudson, Thomas J., Vymetalkova, Veronika, Moreno, Victor, Martín, Vicente, Arndt, Volker, Wei, Wei-Qi, Chung, Wendy, Su, Yu-Ru, Hayes, Richard B., White, Emily, Vodicka, Pavel, Casey, Graham, Gruber, Stephen B., Schoen, Robert E., Chan, Andrew T., Potter, John D., Brenner, Hermann, Jarvik, Gail P., Corley, Douglas A., Peters, Ulrike, Hsu, Li
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477007/
https://ncbi.nlm.nih.gov/pubmed/32758450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.07.006
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