Dimethyl-2-oxoglutarate improves redox balance and mitochondrial function in muscle pericytes of individuals with diabetes mellitus

AIMS/HYPOTHESIS: Treatment of vascular complications of diabetes remains inadequate. We reported that muscle pericytes (MPs) from limb muscles of vascular patients with diabetes mellitus display elevated levels of oxidative stress causing a dysfunctional phenotype. Here, we investigated whether trea...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Faulkner, Ashton, Tamiato, Anita, Cathery, William, Rampin, Andrea, Caravaggi, Carlo Maria, Jover, Eva, Allen, Steve, Mellor, Harry, Hauton, David, Heather, Lisa C., Spinetti, Gaia, Madeddu, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476972/
https://ncbi.nlm.nih.gov/pubmed/32728894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-020-05230-4
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