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Efficacy of GAD-alum immunotherapy associated with HLA-DR3-DQ2 in recently diagnosed type 1 diabetes

AIMS/HYPOTHESIS: The aim of this study was to determine if retention of C-peptide following immunotherapy using recombinant GAD65 conjugated to aluminium hydroxide (GAD-alum) is influenced by HLA risk haplotypes DR3-DQ2 and DR4-DQ8. METHODS: HLA-dependent treatment effect of GAD-alum therapy on C-pe...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Diabetologia
Main Authors: Hannelius, Ulf, Beam, Craig A., Ludvigsson, Johnny
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476912/
https://ncbi.nlm.nih.gov/pubmed/32754804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-020-05227-z
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