Denosumab Therapy for Giant-cell Tumor of the Lumbar Spine: A Case Report and Immunohistochemical Examination

INTRODUCTION: Denosumab, a monoclonal antibody that inhibits the receptor activator of nuclear factor-kappa (RANK) ligand, has been reported to reduce tumor size and progression, promote bone mineralization reconstruction, and increase bone density in patients with giant-cell tumor of bone (GCTB). H...

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Detalhes bibliográficos
Publicado no:J Orthop Case Rep
Main Authors: Yayama, Takafumi, Mori, Kanji, Nakamura, Akira, Mimura, Tomohiro, Imai, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: Indian Orthopaedic Research Group 2020
Assuntos:
Case Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476695/
https://ncbi.nlm.nih.gov/pubmed/32953662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.13107/jocr.2020.v10.i02.1706
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