Diabetes Induced Alterations in Murine Vitreous Proteome Are Mitigated by IL-6 Trans-Signaling Inhibition

PURPOSE: Diabetic retinopathy (DR) is a microvascular complication caused by prolonged hyperglycemia and characterized by leaky retinal vasculature and ischemia-induced angiogenesis. Vitreous humor is a gel-like biofluid in the posterior segment of the eye between the lens and the retina. Disease-re...

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Bibliografske podrobnosti
izdano v:Invest Ophthalmol Vis Sci
Main Authors: Robinson, Rebekah, Youngblood, Hannah, Iyer, Hersha, Bloom, Justin, Lee, Tae Jin, Chang, Luke, Lukowski, Zachary, Zhi, Wenbo, Sharma, Ashok, Sharma, Shruti
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2020
Teme:
Retina
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476668/
https://ncbi.nlm.nih.gov/pubmed/32870245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.61.11.2
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