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Tumor necrosis factor alpha receptor 1 deficiency in hepatocytes does not protect from non-alcoholic steatohepatitis, but attenuates insulin resistance in mice

BACKGROUND: End-stage liver disease caused by non-alcoholic steatohepatitis (NASH) is the second leading indication for liver transplantation. To date, only moderately effective pharmacotherapies exist to treat NASH. Understanding the pathogenesis of NASH is therefore crucial for the development of...

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Bibliografski detalji
Izdano u:World J Gastroenterol
Glavni autori: Bluemel, Sena, Wang, Yanhan, Lee, Suhan, Schnabl, Bernd
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476178/
https://ncbi.nlm.nih.gov/pubmed/32952340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v26.i33.4933
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