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Microstructure and mechanical properties of subchondral bone are negatively regulated by tramadol in osteoarthritis in mice

Objectives: In the treatment of osteoarthritis (OA), tramadol, a common weak opioid, has become popular due to its effectiveness in inhibition of pain. In the present study, we aimed to explore the effect of tramadol on subchondral bone, especially changes in the microstructure and mechanical proper...

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Podrobná bibliografie
Vydáno v:Biosci Rep
Hlavní autoři: Ji, Chen-Chen, Liu, Bo, Shao, Yi-Jie, Liang, Ting, Jiang, Hua-Ye, Chen, Guang-Dong, Luo, Zong-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Portland Press Ltd. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7475645/
https://ncbi.nlm.nih.gov/pubmed/32803252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20194207
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