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Curcumol enhances the anti-tumor effects of metformin via suppressing epithelial-mesenchymal transition in triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is a severe disease with a high mortality rate. Metformin has been found to possess anti-tumor properties. Curcumol, an active ingredient extracted from curcuma, exerts the protective effect in TNBC cells through inducing apoptosis. However, the effec...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Wang, Gangyue, Dong, Yi, Liu, Heng
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7475397/
https://ncbi.nlm.nih.gov/pubmed/32953746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm-20-5438
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