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Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer

Primary prostate tumor heterogeneity is poorly understood, leaving research efforts with challenges regarding the initiation and advancement of the disease. The growth of tumor cells is accompanied by mutations in nuclear and in mitochondrial genomes. Thus, mitochondrial DNA mutations may be used as...

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Détails bibliographiques
Publié dans:Prostate Cancer
Auteurs principaux: Arstad, Christian, Taskén, Kristin, Refinetti, Paulo, Axcrona, Ulrika, Giercksky, Karl-Erik, Ekstrøm, Per Olaf
Format: Artigo
Langue:Inglês
Publié: Hindawi 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474793/
https://ncbi.nlm.nih.gov/pubmed/32908706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7673684
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