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Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer

Primary prostate tumor heterogeneity is poorly understood, leaving research efforts with challenges regarding the initiation and advancement of the disease. The growth of tumor cells is accompanied by mutations in nuclear and in mitochondrial genomes. Thus, mitochondrial DNA mutations may be used as...

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Detalhes bibliográficos
Publicado no:Prostate Cancer
Main Authors: Arstad, Christian, Taskén, Kristin, Refinetti, Paulo, Axcrona, Ulrika, Giercksky, Karl-Erik, Ekstrøm, Per Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474793/
https://ncbi.nlm.nih.gov/pubmed/32908706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/7673684
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